Widetherapeuticindex

由JTamargo著作·2015·被引用251次—Thetherapeuticindex(TI)istherangeofdosesatwhichamedicationiseffectivewithoutunacceptableadverseevents.DrugswithanarrowTI(NTIDs)havea ...,由EJBegg著作·1999·被引用112次—Mostantibiotics,suchastheβ-lactams,macrolidesandquinoloneshaveawidetherapeuticindexandthereforedonotrequiretherapeuticdrugmonitoring.,Thetherapeuticindexisaquantitativemeasurementoftherelativesafet...

Narrow therapeutic index drugs

由 J Tamargo 著作 · 2015 · 被引用 251 次 — The therapeutic index (TI) is the range of doses at which a medication is effective without unacceptable adverse events. Drugs with a narrow TI (NTIDs) have a ...

The therapeutic monitoring of antimicrobial agents

由 EJ Begg 著作 · 1999 · 被引用 112 次 — Most antibiotics, such as the β-lactams, macrolides and quinolones have a wide therapeutic index and therefore do not require therapeutic drug monitoring.

Therapeutic index

The therapeutic index is a quantitative measurement of the relative safety of a drug. It is a comparison of the amount of a therapeutic agent that causes ...

Therapeutic index

The therapeutic index refers to the relationship between a particular drug's toxic and therapeutic dose. It is calculated as the ratio between the two, the ...

Therapeutic Index

2021年6月8日 — Therapeutic Index · Minimum effective concentration (MEC) is the minimum concentration that is required for drug effect · Minimum toxic ...

Therapeutic index estimation of antiepileptic drugs

由 RG Greenberg 著作 · 2016 · 被引用 60 次 — Finally, our estimation of therapeutic index was based on the population therapeutic range, which may be wider than that of an individual. Therefore, we may ...

Therapeutic index

2023年12月12日 — therapeutic index, margin of safety that exists between the dose of a drug that produces the desired effect and the dose that produces ...

Therapeutic Window

Therapeutic window is the time range between injury and treatment during which the treatment is still effective. Time windows for neuroprotective agents that ...